Supplements for Hirsutism: What the Research Shows (2026)

Short answer: No supplement has been shown to reduce hirsutism as well as medical treatment, and none is recommended by the main hirsutism or PMOS guidelines. A handful, including spearmint tea, inositol, NAC, zinc, melatonin and licorice, have small, short studies showing changes in hormones, and a few reported modest changes in hair scores. Most popular options, such as saw palmetto, DIM, maca, evening primrose oil and apple cider vinegar, have no studies on unwanted hair at all.

From our survey: The most-tried supplements among women with PCOS were progesterone (32%), spearmint (26%) and zinc (15%), but few said they clearly worked. See what women told us vs. the evidence.

If you have hirsutism, you have probably seen long lists of “anti-androgen” supplements promising to balance your hormones. It makes sense to want something natural, cheap and without a prescription. The problem is that most of these lists are written to sell products, not to tell you what the research shows.

So we went through the studies supplement by supplement. For each one, we checked whether it has been tested in people, whether those studies measured hair growth or only hormone levels, and how big and well designed they were. We also cover safety, because “natural” does not mean harmless.

A quick note on names: PMOS (formerly PCOS) is the new name for polycystic ovary syndrome, agreed in a global consensus published in The Lancet in May 2026 ^[1]. PMOS is the most common cause of hirsutism. Many studies below were done before the name change, so they refer to “women with PCOS”.

Supplements for hirsutism at a glance

This table summarizes what we found. The evidence labels are explained in the next section, and each supplement has its own section further down.

Supplement	What was studied	Evidence	Bottom line
Spearmint tea	Small trials, including a 30-day RCT in 42 women with PCOS	Limited	Lowered testosterone in 30 days; doctor-rated hair scores did not change
Inositol (myo-inositol)	Many RCTs in PCOS, pooled in a 2024 review	Limited	Some metabolic benefit; metformin did better for hirsutism
NAC (N-acetylcysteine)	RCTs in PCOS, mostly for fertility	Limited	No better than placebo for hirsutism in a meta-analysis
Zinc	One 8-week RCT in 48 women with PCOS	Limited	Small drop in hair scores, but the trial is under editorial investigation
Melatonin	One 12-week RCT in 56 women with PCOS	Limited	Small drop in hair scores and testosterone; not yet repeated
Licorice	Tiny study in 9 healthy women	Limited	Lowered testosterone; raises blood pressure risk
White peony	Lab studies and herbal mixtures	None	No hair outcomes in people
Vitamin D	Several small trials in PCOS	Limited	May lower testosterone; no clear effect on hair scores
Omega-3 fish oil	Meta-analysis of 9 RCTs in PCOS	Limited	Helps some metabolic markers; no hair benefit shown
Cinnamon	Small RCTs in PCOS	None	No change in androgens; mixed results for periods
Green tea / EGCG	Lab studies; small PCOS trials	None	No hair outcomes; extracts can harm the liver
Magnesium	No trials of magnesium alone on hirsutism	None	Only useful if you are low
Vitamins A, E, B6, copper	No hirsutism studies	None	No evidence they reduce hair
Saw palmetto	Prostate trials in men	None	Did not beat placebo even for prostate symptoms
Chaste tree (vitex)	Prolactin and PMS studies	None	No hirsutism studies
Black cohosh	Ovulation and menopause studies	None	No hirsutism studies; rare liver injury
Evening primrose oil	Eczema, PMS and breast pain studies	None	No evidence for any condition, including hair
Maca, reishi, DIM	Lab studies or none	None	No human studies on hirsutism
Nettle root, dandelion root	No hirsutism studies	None	No evidence
Aloe vera, apple cider vinegar, black molasses	Skin, blood sugar or no studies	None or Limited	Do not reduce hair growth

How we graded the evidence

We gave each supplement one of four labels. “Strong” means guidelines recommend it or several good trials agree. “Moderate” means at least one decent randomized controlled trial (RCT), where people are randomly assigned to the supplement or a dummy pill. “Limited” means small, short or uncontrolled human studies, or only indirect evidence such as a change in hormone levels. “None” means there are no human studies on hirsutism or androgens, only lab or animal data, or nothing at all.

No supplement earned “Strong” or “Moderate”. A 2017 systematic review of 24 RCTs of supplements and herbal medicines in women with PCOS found no study at low risk of bias and concluded there was no high-quality evidence that any of them work ^[2].

Two things are worth keeping in mind as you read:

• Lower testosterone is not the same as less hair. Many studies only measured blood hormones. Hair follicles respond slowly, and a lab change does not guarantee you will see a difference in the mirror.
• Hair takes months to respond. Even proven medicines need time. The Endocrine Society suggests trying a treatment for at least 6 months before changing it ^[3]. Most supplement studies lasted 1 to 3 months.

For comparison, the Endocrine Society guideline suggests birth control pills as the first treatment for most women with hirsutism, with an anti-androgen added if hair is still bothersome after 6 months, plus hair removal if wanted. It does not recommend any supplement ^[3]. Read more in our guide to hirsutism medication.

Supplements with some human evidence

Spearmint

Evidence: Limited Spearmint tea is the best-known herbal remedy for hirsutism. In a 30-day RCT of 42 women with PCOS, two cups of spearmint tea a day lowered free and total testosterone compared with a placebo tea. Women rated their hair as improved, but the doctor-rated Ferriman-Gallwey hair score did not change significantly ^[4]. The trial was likely too short to show a change in hair. We cover the studies, tea versus capsules, and safety in our full article on spearmint for hirsutism.

Inositol (myo-inositol)

Evidence: Limited Inositol is a sugar-like compound involved in how cells respond to insulin. Myo-inositol and D-chiro-inositol are popular in the PMOS community. A 2024 systematic review done for the international PCOS guideline found some benefits for metabolic measures, but concluded that the evidence for inositol is “limited and inconclusive”. Metformin, a diabetes medicine, may work better than inositol for hirsutism, although inositol causes fewer stomach side effects ^[5].

The 2023 international PCOS guideline says inositol can be considered based on personal preference, but that its benefits for hirsutism are limited and no specific type, dose or combination can be recommended. It encourages women who take inositol or other complementary therapies to tell their healthcare professional ^[6].

Does NAC help with hirsutism?

Evidence: Limited NAC (N-acetylcysteine) is an amino acid supplement that helps the body make glutathione, an antioxidant. In a 24-week RCT, 100 women with PCOS took either NAC or metformin. Hirsutism scores, free testosterone and insulin levels fell in both groups by similar amounts ^[7]. There was no placebo group, though, and metformin itself is not recommended for hirsutism because it did no better than placebo in the Endocrine Society’s analysis ^[3].

A 2015 meta-analysis of 8 RCTs (910 women) found NAC improved ovulation and pregnancy rates compared with placebo, but it made no significant difference to testosterone, hirsutism or acne. Several of the trials had a high risk of bias ^[8]. So NAC may have a role in fertility treatment, but it is not a good bet for unwanted hair.

Does zinc help with hirsutism?

Evidence: Limited Zinc is often said to block 5-alpha reductase, the enzyme that turns testosterone into the stronger hormone DHT in hair follicles. In one RCT, 48 women with PCOS took 50 mg of zinc or a placebo for 8 weeks. Hirsutism scores dropped slightly more with zinc, and scalp hair loss improved, but hormone levels did not change ^[9]. In 2020 the journal added a notice that its editors are investigating this article because of concerns about the trial ^[9]. Another trial from the same research group, which tested magnesium, zinc, calcium and vitamin D together, was retracted in 2023 ^[10].

Adult women need 8 mg of zinc a day, and most people get this from food such as meat, shellfish, beans and nuts. The upper limit for adults is 40 mg a day. The 50 mg dose used in the trial is above that limit, and taking 50 mg or more for weeks can cause copper deficiency and weaken the immune system ^[11]. Don’t take high-dose zinc without talking to your doctor.

Does melatonin help with hirsutism?

Evidence: Limited Melatonin is the hormone that helps regulate your sleep-wake cycle. In a 12-week RCT, 56 women with PCOS took 5 mg of melatonin twice a day or a placebo. Hirsutism scores and total testosterone fell slightly more with melatonin ^[12]. This is a single trial that has not been repeated, and it comes from the same research group as the zinc trial above. Until other teams confirm it, we would not take melatonin for hair growth. If you have trouble sleeping, talk to your doctor about whether melatonin is right for you.

Do white peony and licorice help with hirsutism?

Evidence: Limited Licorice: In a small study of 9 healthy women, a licorice preparation taken daily for two menstrual cycles lowered total testosterone, which returned to normal after stopping. There was no control group, and hair growth was not measured ^[13]. Researchers think compounds in licorice block enzymes that make testosterone ^[13]. A 2014 review found only weak clinical evidence for licorice combined with spironolactone in women with PCOS ^[14].

Licorice has real risks. Glycyrrhizin, a compound in licorice root, can cause high blood pressure and, with large or long-term use, irregular heartbeat and even cardiac arrest. People with high blood pressure or heart or kidney disease are most at risk, and large amounts are unsafe in pregnancy ^[15].

Evidence: None White peony: White peony (Paeonia lactiflora) is used in traditional Chinese and Japanese medicine, often combined with licorice. Lab research suggests it may promote the conversion of testosterone to estrogen ^[16]. Clinical studies have tested it only as part of herbal formulas, and the 2014 review called the clinical evidence for herbal medicines in PCOS “variable” ^[14]. We could not find any study showing that white peony alone reduces unwanted hair.

Omega-3 fish oil

Evidence: Limited Omega-3 fatty acids are found in oily fish and fish oil supplements. A meta-analysis of 9 RCTs with 591 women with PCOS found that omega-3 improved insulin resistance, cholesterol and triglycerides ^[17]. Its summary did not report any effect on androgens or hair growth. Omega-3 may support your overall metabolic health if you have PMOS, but there is no evidence it reduces hirsutism.

What vitamins help to reduce facial hair?

No vitamin has been shown to reduce facial or body hair. A healthy diet matters for your overall health, and some women with PMOS are low in certain nutrients, but correcting a deficiency is different from treating hirsutism. Here is what we found for the vitamins and minerals most often recommended online. For food, see our article on foods and facial hair growth.

Vitamin D

Evidence: Limited A 2024 meta-analysis of 6 trials (445 women with PCOS, all in Iran) found that vitamin D supplements lowered total testosterone. The improvement in hirsutism scores was not statistically significant ^[18]. An earlier review of hirsutism treatments listed vitamin D among therapies without enough evidence to support their use ^[19]. If a blood test shows you are low in vitamin D, it makes sense to treat that for your general health.

Does magnesium help with hirsutism?

Evidence: None Magnesium is a mineral involved in hundreds of processes, including blood sugar control. We found no trials of magnesium alone that measured hirsutism. The one trial that combined magnesium with zinc, calcium and vitamin D and reported hormone changes in women with PCOS was retracted ^[10].

Low magnesium intake is common: 48% of Americans get less than they need from food. Women aged 19 to 30 need 310 mg a day and women aged 31 to 50 need 320 mg, mostly from foods such as greens, beans, nuts and whole grains. Supplements should stay under 350 mg a day, because higher doses commonly cause diarrhea, nausea and cramps ^[20].

Vitamins A, E, B6 and copper

Evidence: None Some articles claim that vitamin A regulates testosterone, vitamin B6 lowers prolactin, and copper balances hormones. We could not find any studies showing that these nutrients reduce hirsutism or androgen levels in women. Vitamin E and vitamin A creams can help moisturize skin after hair removal, but they won’t change how fast hair grows back. Don’t take high-dose vitamins or minerals unless your doctor recommends them.

Popular herbs with little or no evidence

The following supplements are often sold as “natural anti-androgens”. Some have interesting lab results, but none have been tested in women with hirsutism.

Does green tea help with hirsutism?

Evidence: None Green tea contains catechins such as EGCG, which inhibit 5-alpha reductase in lab studies ^[16]. In the 2017 review of RCTs in PCOS, green tea did not significantly reduce missed periods compared with placebo ^[2]. We found no studies showing it reduces unwanted hair. Drinking green tea is safe for most adults, but green tea extract pills have been linked to rare liver injury and can interact with some medicines, such as the blood pressure drug nadolol ^[21].

Does saw palmetto help with hirsutism?

Evidence: None Saw palmetto is sold as an anti-androgen because it is used for prostate problems in men. But a 2023 review of 27 studies found little or no benefit for prostate symptoms, and two NIH-funded trials found no improvement even at three times the usual dose ^[22]. In clinical trials it has not performed better than placebo ^[16]. There are no studies in women with hirsutism. It may be unsafe in pregnancy and while breastfeeding ^[22].

Does chaste tree (vitex) help with hirsutism?

Evidence: None Chaste tree, also called chasteberry or vitex, is thought to lower prolactin, a hormone made by the pituitary gland ^[16]. Low-to-moderate quality studies suggest it might ease premenstrual breast pain ^[23]. There are no studies on hirsutism. It may be unsafe in pregnancy and for women with hormone-sensitive conditions such as breast cancer ^[23]. If you have high prolactin, see a doctor, because it needs a medical cause to be ruled out.

Does black cohosh help with hirsutism?

Evidence: None Black cohosh is mainly used for menopause symptoms, and a 2023 review found it may help with hot flashes ^[24]. In women with PCOS, it has been studied for ovulation alongside fertility drugs, not for hair ^[14]. There is no evidence it reduces hirsutism. Rare but serious liver injury has been reported, so watch for dark urine or tiredness and stop if they appear. It may not be safe in pregnancy ^[24].

Does evening primrose oil help with hirsutism?

Evidence: None Evening primrose oil is rich in gamma-linolenic acid (GLA), an omega-6 fat. The National Center for Complementary and Integrative Health says there is not enough evidence to support it for any health condition. It did not relieve eczema, worked no better than placebo for breast pain, and the evidence for PMS and menopause is insufficient ^[25]. We found no studies showing it prevents hair growth or helps hirsutism, and claims that it does are unsupported. Side effects are usually mild stomach upset ^[25].

Does maca help with hirsutism?

Evidence: None Maca is a root vegetable from Peru, sold as a powder or capsules and promoted for libido and energy. We found no studies of maca in women with hirsutism or high androgens. Stories about maca reducing facial hair are anecdotes, and many products combine it with other ingredients, so it is impossible to know what had an effect.

Does reishi mushroom help with hirsutism?

Evidence: None Red reishi (Ganoderma lucidum) has been reported to reduce 5-alpha reductase activity in lab research ^[16]. We found no studies in women with hirsutism or high androgens. As with any supplement, check with your doctor first if you take other medicines.

Does DIM help with hirsutism?

Evidence: None DIM (diindolylmethane) is formed when your body breaks down indole-3-carbinol, a compound in broccoli, cabbage and kale. It is marketed to “balance estrogen”. We found no studies of DIM in women with hirsutism or PMOS, and no evidence it lowers androgens in women.

Does nettle root help with hirsutism?

Evidence: None Stinging nettle root is mostly sold for prostate symptoms in men. We found no studies on hirsutism or androgen levels in women. Nettle leaf and nettle root are also different products, which adds to the confusion online.

Does dandelion root help with hirsutism?

Evidence: None Dandelion root is used in herbal teas and traditional medicine for digestion. There are no studies on dandelion and hirsutism or androgens. Drinking the tea is unlikely to cause harm for most people, but it won’t reduce hair growth.

Kitchen remedies

Does apple cider vinegar help with hirsutism?

Evidence: Limited The only study we found gave 7 women with PCOS a daily vinegar drink for about 3 months. Insulin resistance improved in 6 of them and 4 had ovulatory periods again. There was no comparison group and hair growth was not measured ^[26]. That is far too little to say apple cider vinegar helps hirsutism.

Does cinnamon help with hirsutism?

Evidence: None In a 6-month RCT of 45 women with PCOS, cinnamon capsules improved the number of menstrual cycles compared with placebo, but androgen levels did not change and many women dropped out ^[27]. When the 2017 review pooled cinnamon trials, it found no difference in periods compared with placebo ^[2]. No study has shown cinnamon reduces hair. Cassia cinnamon, the most common type, contains coumarin, which can affect the liver in large amounts ^[28].

Does black molasses help with hirsutism?

Evidence: None Blackstrap molasses is a byproduct of sugar refining. There are no studies on molasses and hirsutism or hormones. It is still a form of sugar, which is worth keeping in mind if you have insulin resistance.

Does aloe vera help with hirsutism?

Evidence: None Aloe vera does not reduce or prevent hair growth, and no studies have tested it for hirsutism. As a gel on the skin, it is generally well tolerated, and research suggests it may help burns heal ^[29]. Many people use it to soothe skin after shaving or waxing. Don’t take aloe by mouth: The FDA removed aloe latex from over-the-counter laxatives, whole-leaf extract has been linked to cancer in animal studies, and oral aloe may be unsafe in pregnancy ^[29]. For skin care after hair removal, see our guide to razor bumps and ingrown hairs.

What about progesterone cream and essential oils?

Progesterone cream and lavender and tea tree oils also appear on many supplement lists for hirsutism. Progesterone is a hormone, not a supplement, and there is little evidence it helps hirsutism. We cover it in our article on the best over-the-counter anti-androgen. For the small study on lavender and tea tree oils, see our guide to essential oils for facial hair.

How to use supplements safely

If you decide to try a supplement, these points can help you do it more safely:

• Supplements are not regulated like medicines. In the US, the FDA does not approve supplements before they are sold, and products don’t have to prove they work. Labels don’t always match what is inside, and the FDA has found hidden prescription drugs in some products. Words like “standardized” or “certified” do not guarantee quality ^[30].
• Tell your doctor and pharmacist. Supplements can interact with medicines, increase bleeding risk or affect anesthesia during surgery ^[30]. Licorice, for example, can interact with corticosteroids ^[15].
• Be careful if you could become pregnant. Many supplements have never been tested in pregnancy ^[30]. Licorice, saw palmetto, chaste tree, black cohosh and oral aloe may be unsafe in pregnancy ^{[15] [22] [23] [24] [29]}.
• Try one at a time. If you take several products at once, you won’t know which one helped or caused side effects.
• Give it a fair trial, then stop if nothing changes. Hair responds slowly, so judge any treatment over months, not weeks ^[3]. Take a photo or score yourself with our hirsutism self-check before you start.
• Don’t replace treatment that works. Supplements should not delay finding the cause of your hair growth or replace medicine your doctor has prescribed.

If you want an approach that doesn’t involve medication, our article on natural remedies for hirsutism covers lifestyle changes, which have better evidence than most supplements.

When to see a doctor

Hirsutism is usually caused by PMOS, but it can also be a sign of other hormonal conditions, so it is worth getting checked before you start buying supplements. See what causes hirsutism for the full list. See a doctor soon if you notice:

• Hair growth that started suddenly or is getting worse quickly
• A deeper voice, an enlarged clitoris, more muscle or male-pattern hair loss, which are signs of virilization
• Irregular, very infrequent or missing periods
• Possible side effects from a supplement, such as dark urine, unusual tiredness or a racing or irregular heartbeat

Sudden or rapidly worsening hair growth with signs of virilization can point to a hormone-producing tumor, which is rare but needs prompt tests ^[3].

Go deeper: Inositol for hirsutism · Insulin resistance and facial hair

Frequently asked questions

What is the best supplement for hirsutism?

There is no supplement with good evidence for reducing unwanted hair. Spearmint tea and inositol are the best studied, but even they have only limited evidence ^{[4] [5]}. Birth control pills, anti-androgen medicines and hair removal work better ^[3].

Can supplements lower testosterone in women?

Some small studies found that spearmint tea, licorice, melatonin and vitamin D lowered testosterone ^{[4] [13] [12] [18]}. But lower testosterone in a blood test did not reliably lead to less hair in these studies, and none has been confirmed in large trials.

How long do supplements take to work for hirsutism?

Hair follicles respond slowly, and even proven medicines are judged after at least 6 months ^[3]. Most supplement studies lasted only 1 to 3 months, so they could not show long-term effects on hair.

Are supplements for hirsutism safe?

Not always. Licorice can raise blood pressure, green tea extract and black cohosh have been linked to rare liver injury, and high-dose zinc can cause copper deficiency ^{[15] [21] [24] [11]}. Supplements are not checked by the FDA before sale, so quality varies ^[30].

Can I take supplements with spironolactone or the pill?

Ask your doctor or pharmacist first. Some supplements interact with medicines ^[30], and licorice in particular can raise blood pressure ^[15]. If you are on an anti-androgen such as spironolactone, you need reliable contraception, whatever supplements you take ^[6].

Key takeaways

• No supplement has strong or moderate evidence for reducing hirsutism, and no guideline recommends one.
• Spearmint, inositol, NAC, zinc, melatonin, licorice and vitamin D have small studies, mostly showing hormone changes rather than less hair.
• Saw palmetto, chaste tree, black cohosh, evening primrose oil, maca, reishi, DIM, nettle, dandelion, aloe vera, apple cider vinegar and black molasses have no evidence for hirsutism.
• “Natural” is not the same as safe: Some supplements affect blood pressure, the liver or pregnancy, and quality is not regulated.
• Get the cause checked first, and talk to a doctor about treatments that are proven to work.

Sources

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This article is for education and is not medical advice. Talk to a doctor about diagnosis and treatment.